Research in IMO
Ongoing projects
Comprehensive analysis of the ABCA4 gene: characterization of new pathogenic variants
A great number of patients affected by retinal dystrophies with macular involvement, such as Stargardt's disease, have mutations in ABCA4, a complex and large gene. The aim of this research is to study this gene to improve the diagnosis and treatment of these pathologies.
GTSCOPE
A study desease progression in genetically define subjects with geographic atrophy secondary to Age-Related Macular Degeneration
KOWA
A Double-Masked, Randomised, Placebo-Controlled, Parallel-Group, 12-Week, Phase 2 Study to Investigate the Safety and Efficacy of Ripasudil (K-321) Eye Drops After Descematorhexis in Patients with Fuchs Endothelial Corneal Dystrophy
Project history
Mass sequencing of exomes for the identification of new genes and variants responsible for retinal dystrophies
Retinitis pigmentosa, with a prevalence of 1 in 4,000 people and more than one million sufferers worldwide, is the most common retinal dystrophy. These diseases are neurodegenerative and caused by the death of the photoreceptors and cells of the retinal pigment epithelium.
Artemis
Efficacy and safety of slow-release bimatoprost in patients with open-angle glaucoma or ocular hypertension.