Research is the main activity of the IMO Foundation. By combining basic research and clinical research, and through an unique model where geneticists and ophthalmologists work together, we seek the progress of ophthalmology in order to find a solution to ocular pathologies for which there is still no cure.
Research in IMO
The IMO is at the forefront of research into the latest developments and contributes to the main clinical trials of the day as a member of the EVICR (European Vision Institute Clinical Research Network). The IMO’s leadership and innovative approach are also reflected in a unique and pioneering commitment to translational research, in which ophthalmologists and geneticists work side by side to advance faster in the prevention, diagnosis and treatment of hereditary eye diseases.
Ongoing projects
On this page you will find the ongoing projects that IMO Foundation is currently developing.
In the field of clinical research, the aim of the projects currently under development is not only to continue improving the prognosis of patients with certain pathologies, but also to offer, for the first time, effective solutions to diseases that currently have no treatment. This is also the ultimate goal of the basic research projects, which aim to analyze in depth already known genes, as well as to identify new genes related to hereditary eye diseases.
Investigación básica
Identification of new genetic variants responsible for Stickler Syndrome
The Stickler Syndrome encompasses several genetic diseases, which cause various eye disorders and are difficult to diagnose. For this reason, the objective of this research is to identify all the genes involved in these pathologies in order to improve the process of diagnosis and treatment.
Investigación clínica
IN-SIGHT
Efficacy and safety assessment of T4032 (unpreserved bimatoprost 0.01%) versus Lumigan 0.01% in ocular hypertensiove or glacomatous patients
Investigación clínica
Holocore
Efficacy and safety of autologous cultivated limbal stem cells transplantation (ACLSCT) for restoration of corneal epithelium in patients with limbal stem cell deficiency.
Project history
On this page you will find the project history that the IMO Foundation has developed since its inception.
IMO's ophthalmologists, optometrists and nurses who specialise in ocular photography conduct several multi-centre clinical trials each year. These studies are in addition to the basic research projects pioneered by the Molecular Biology Laboratory.
Investigación básica
Mass sequencing of exomes for the identification of new genes and variants responsible for retinal dystrophies
Retinitis pigmentosa, with a prevalence of 1 in 4,000 people and more than one million sufferers worldwide, is the most common retinal dystrophy. These diseases are neurodegenerative and caused by the death of the photoreceptors and cells of the retinal pigment epithelium.
Investigación clínica
NEUTON
Phase IV clinical trial to evaluate the efficacy of aflibercept in Naïve patients with macular edema secondary to central retinal vein occlusion (CRVO) in Treat and extend (TAE) individualized treatment regimen.
