Evaluation of the effectiveness of aflibercept intravitreous injection (IVT) in clinical practice in non treated patients with Neovascular Age-Related Macular Degeneration.
Long-term safety and follow-up study after autologus cultivated limbal stem cells transplantation for restoretion of corneal epithelium in patients with limbal stem deficiency due to ocular burns.
Clinica evaluations of the clinical performance of Phakic IOL.
Evaluation of the effectiveness and security of umbilical cord blood eyedrops for the treatment of neurotrophic keratitis.
Clinical trial to evaluate the effects of Fydrane® and standard topical mydriatics and anaesthetics protocol on ocular surface after cataract surgery.
Influence of posterior vitreous detachment on retinal detachment after lens surgery in myopic eyes.
Prospective, feasibility study to evatuate the safety of the EndoArt for treatment of subjects suffering from corneal edema.
Performance and safety assessment of t4020 combined with standard post-operative therapy versus standard post-operative therapy in managing corneal epithelial defect following epi-off accelerated corneal cross-linking.
A double-masekd study of SYL1001 in patients with moderate to dry eye disease (DED)
An open-label, randomized, active-controlled, parallel-group, Phase-3b study of the efficacy, safety, and tolerability of three different treatment regimens of 2 mg aflibercept administered by intravitreal injections to subjects with diabetic macular edema (DME)
Ensayo fase IV para evaluar la eficacia de aflibercept en pacientes Naïve con edema macular secundario a Oclusión de la vena central de la retina (OVCR) en régimen de tratamiento indiviualizado Treat and extend (TAE).
Mass sequencing of exomes for the identification of new genes and variants responsible for retinal dystrophies
Retinitis pigmentosa, with a prevalence of 1 in 4,000 people and more than one million sufferers worldwide, is the most common retinal dystrophy. These diseases are neurodegenerative and caused by the death of the photoreceptors and cells of the retinal pigment epithelium.
Identification of new retinal dystrophy genes and characterisation of genotype/phenotype correlations
Retinal dystrophies (RD) are a heterogeneous group of hereditary diseases that are characterised by the degenerative effect that they have on the photoreceptors and cells of the retinal pigment epithelium.
The vast majority of patients with Stargardt disease, as well as half of recessive cone and rod dystrophy cases, have ABCA4 gene mutations.
Phase III, multicentre, randomised, double-blind, sham-controlled trial to assess the efficacy and safety of lampalizumab administered by intravitreal injection to patients with geographic atrophy secondary to age-related macular degeneration.
Phase IV: Prevention of macular oedema in cataract surgery. PREMED. Non-commercial research.
Phase III: Two-year, randomised, double-blind, multicentre, two-group trial comparing the efficacy and safety of 6 mg RTH258 compared to aflibercept in subjects with wet age-related macular degeneration.
Efficacy and safety of slow-release bimatoprost in patients with open-angle glaucoma or ocular hypertension.
Randomised, active-controlled, parallel group, phase III trial on the efficacy, safety and tolerability of 2 mg aflibercept administered with intyravidial injections using two different regimens of treatment for subjects with neovascular age-related macular degeneration.
Safety and efficacy of abiciparpegol (AGN-150998) in patients with neovascular age-related macular degeneration.
Randomised, parallel-group, multicentre, blind to evaluators clinical trial to assess the efficacy and safety of PRGF-Endoret eye drops in patients with stage 2 and 3 neurotrophic keratitis.
Phase II, multicentre, randomised, double-masked, 4 parallel arms, controlled, 6-month trial designed to evaluate the safety and efficacy of PAD ciclosporin (CsA 0.06% and 0.03%) ophthalmic dispersion administered once daily in combination with lubricant therapy and a 3-month post-treatment safety follow-up in moderate to severe dry eye patients.
Phase IV, randomised, double-blind trial with simulated control for the analysis of the efficacy, safety and tolerability of aflibercept intravenous monotherapy compared to aflibercept and concomitant photodynamic therapy in patients with polypodal choroidal vasculopathy.
Compensation for blindness with the Intelligent Retinal Implant System (IRIS V2) in patients with retinal dystrophy.
Efficacy and safety of autologous cultivated limbal stem cells transplantation (ACLSCT) for restoration of corneal epithelium in patients with limbal stem cell deficiency.
Investigation of AcrySof® IQ PanOptix™ Presbyopia-Correcting Intraocular Lens (IOL) Model TFNT00.