Research in IMO
Ongoing projects
Identification of new genetic variants responsible for Stickler Syndrome
The Stickler Syndrome encompasses several genetic diseases, which cause various eye disorders and are difficult to diagnose. For this reason, the objective of this research is to identify all the genes involved in these pathologies in order to improve the process of diagnosis and treatment.
MYOPRED
Influence of posterior vitreous detachment on retinal detachment after lens surgery in myopic eyes.
PRGF-Endoret
Randomised, parallel-group, multicentre, blind to evaluators clinical trial to assess the efficacy and safety of PRGF-Endoret eye drops in patients with stage 2 and 3 neurotrophic keratitis.
Project history
Mass sequencing of exomes for the identification of new genes and variants responsible for retinal dystrophies
Retinitis pigmentosa, with a prevalence of 1 in 4,000 people and more than one million sufferers worldwide, is the most common retinal dystrophy. These diseases are neurodegenerative and caused by the death of the photoreceptors and cells of the retinal pigment epithelium.
Harrier
Phase III: Two-year, randomised, double-blind, multicentre, two-group trial comparing the efficacy and safety of 6 mg RTH258 compared to aflibercept in subjects with wet age-related macular degeneration.