Research in IMO
Ongoing projects
Comprehensive analysis of the ABCA4 gene: characterization of new pathogenic variants
A great number of patients affected by retinal dystrophies with macular involvement, such as Stargardt's disease, have mutations in ABCA4, a complex and large gene. The aim of this research is to study this gene to improve the diagnosis and treatment of these pathologies.
ENDOART
Prospective, feasibility study to evatuate the safety of the EndoArt for treatment of subjects suffering from corneal edema.
BST- Cordó umbilical
Evaluation of the effectiveness and security of umbilical cord blood eyedrops for the treatment of neurotrophic keratitis.
Project history
Mass sequencing of exomes for the identification of new genes and variants responsible for retinal dystrophies
Retinitis pigmentosa, with a prevalence of 1 in 4,000 people and more than one million sufferers worldwide, is the most common retinal dystrophy. These diseases are neurodegenerative and caused by the death of the photoreceptors and cells of the retinal pigment epithelium.
Aqua
Open-label phase IV trial to examine the change of vision-related quality of life in subjects with diabetic macular oedema (DMO) during treatment with intravitreal injections of 2 mg aflibercept according to EU label for the first year of treatment.